ISTH News  45 Total

Scientific News  19 Total

Superior efficacy and reduced transfusions with 4F-PCC vs. FP in cardiac surgery: LEX-211 (FARES-II)

Superior efficacy and reduced transfusions with 4F-PCC vs. FP in cardiac surgery: LEX-211 (FARES-II)

June 24, 2025 | Jeannie Callum, M.D.; Kingston Health Sciences Centre and Queen's University; Kingston, Ontario, Canada
Molecular basis of vitamin K-driven gamma-carboxylation regulating hemostasis at membrane interface

Molecular basis of vitamin K-driven gamma-carboxylation regulating hemostasis at membrane interface

June 24 | Weikai Li, Ph.D.; Washington University School of Medicine; St. Louis, MO, U.S.
Platelets promote thrombo-inflammation and glomerular endothelial dysfunction in diabetic kidneys

Platelets promote thrombo-inflammation and glomerular endothelial dysfunction in diabetic kidneys

June 24, 2025 | Anubhuti Gupta, M.Tech.; University Hospital Leipzig; Leipzig, Germany
Critical role of fibrinolysis in hematopoietic recovery after myelosuppression

Critical role of fibrinolysis in hematopoietic recovery after myelosuppression

June 23, 2025 | Lakmali M. Silva, Ph.D.; Harvard School of Dental Medicine, Harvard University; Boston, MA, U.S.
DOCK2 regulates platelet biogenesis and functions by controlling cytoskeletal actin dynamics

DOCK2 regulates platelet biogenesis and functions by controlling cytoskeletal actin dynamics

June 23, 2025 | Chao Fang, Ph.D.; Huazhong University of Science and Technology; Wuhan, China
Glucagon-like peptide 1 receptor agonists and venous thromboembolism in patients with obesity

Glucagon-like peptide 1 receptor agonists and venous thromboembolism in patients with obesity

June 23, 2025 | Cho Han Chiang, M.D., M.M.Sc.; Mount Auburn Hospital/Harvard Medical School; Cambridge, MA, U.S.; and Rushad Patell, M.B.B.S.; Beth Israel Deaconess Medical Center; Boston, MA, U.S.

Micrometer-scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy

Micrometer-scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy

June 23, 2025 | Keith Neeves, Ph.D.; University of Colorado; Denver, CO, U.S.
Management of immune TTP without plasma exchange: lessons learned from the Austrian experience

Management of immune TTP without plasma exchange: lessons learned from the Austrian experience

June 23, 2025 | Paul Knoebl, M.D.; Medical University of Vienna; Vienna, Austria
Age-adjusted D-dimer cut-off levels to rule out DVT: the ADJUST-DVT management outcome study

Age-adjusted D-dimer cut-off levels to rule out DVT: the ADJUST-DVT management outcome study

June 23, 2025 | Grégoire Le Gal, M.D., Ph.D.; University of Ottawa; Ottawa, ON, Canada
Mechanistic insights into detrimental VWF activity during stroke

Mechanistic insights into detrimental VWF activity during stroke

June 23, 2025 | Frederik Denorme, Ph.D.; Washington University; St. Louis, MO U.S.
Predicting joint damage in non-severe hemophilia A using machine learning

Predicting joint damage in non-severe hemophilia A using machine learning

June 23, 2025 | Ana Marco-Rico, M.D., Ph.D.; University General Hospital Dr. Balmis; Alicante, Spain
Rivaroxaban versus enoxaparin in pediatric venous thromboembolism: experience in a hemostasis center

Rivaroxaban versus enoxaparin in pediatric venous thromboembolism: experience in a hemostasis center

June 22, 2025 | Maria Landwehr Lardelli, M.D.; Vall d'Hebron University Hospital; Barcelona, Spain

Essential role of VWF-aIIbß3 binding in thrombus stability in vessel injury

Essential role of VWF-aIIbß3 binding in thrombus stability in vessel injury

June 22, 2025 | Qizhen Shi, M.D., Ph.D.; Medical College of Wisconsin and Versiti Blood Research Institute; Milwaukee, WI, U.S.

Edoxaban for the treatment of pediatric venous thromboembolism: phase 3 randomized controlled trial

Edoxaban for the treatment of pediatric venous thromboembolism: phase 3 randomized controlled trial

June 22, 2025 | Mihir Bhatt, M.D., M.Sc.; McMaster Children's Hospital, McMaster University; Hamilton, ON, Canada
Clonal hematopoiesis of indeterminate potential in coronary disease patients: a 24-year follow-up

Clonal hematopoiesis of indeterminate potential in coronary disease patients: a 24-year follow-up

June 22, 2025 | Cynthia Carbonneau, M.D., Ph.D.; Centre Hospitalier Universitaire de Lille; Lille, France

Caplacizumab and immunosuppression without plasma exchange in thrombotic thrombocytopenic purpura

Caplacizumab and immunosuppression without plasma exchange in thrombotic thrombocytopenic purpura

June 22, 2025 | Paul Coppo, M.D., Ph.D.; Saint-Antoine Hospital, Sorbonne University; Paris, France

Phase 3 study of rurioctocog alfa pegol in previously untreated patients with severe hemophilia A

Phase 3 study of rurioctocog alfa pegol in previously untreated patients with severe hemophilia A

June 22, 2025 | Robert Sidonio, Jr., M.D., M.Sc.; Hemophilia of Georgia Center for Bleeding and Clotting Disorders of CHOA; Atlanta, GA, U.S.

Comparison of bleeding risk between rivaroxaban and apixaban in acute venous thromboembolism

Comparison of bleeding risk between rivaroxaban and apixaban in acute venous thromboembolism

June 22, 2025 | Lana Castellucci, M.D.; University of Ottawa, Ottawa Hospital; Ottawa, ON, Canada
Novel dual-action fusion proteins combining truncated ADAMTS13 and a nanobody against VWF

Novel dual-action fusion proteins combining truncated ADAMTS13 and a nanobody against VWF

June 21, 2025 | Yunpeng Xue, M.Sc.; Synapse Research Institute; Maastricht, the Netherlands