Scientific Interviews - ISTH Congress Daily 2021

Pathogenic Factor XII Mutations: Form Dertermines Dysfunction

Sunday, July 18, 2021

Factor XII (FXII) drives intrinsic coagulation and bradykinin production when blood contacts unnatural surface materials. It was identified as a potential therapeutic target for thrombosis with a desirable safety profile.

Controlled Long-Term Knockdown of Plasminogen in Mice and Dogs Using siRNA: Assessment of Phenotype and Toxicity

Sunday, July 18, 2021

The fibrinolytic system, and in particular the protease plasmin, play an important role in the maintenance of vascular patency by dissolving fibrin‐rich thrombi.

Role of DOAC in PAD

Sunday, July 18, 2021

Peripheral artery disease (PAD) commonly refers to atherosclerosis of the lower extremities and is associated with atherosclerotic disease in other vascular territories.

Impact of Novel Therapies Around the World

Sunday, July 18, 2021

Currently, prophylaxis is recognized as the standard of care for hemophilia. The development of non-replacement therapies led to a considerable achievement in the management of severe hemophilia patients.

Pathogenic Factor XII Mutations: Form Dertermines Dysfunction

Controlled Long-Term Knockdown of Plasminogen in Mice and Dogs Using siRNA: Assessment of Phenotype and Toxicity

Role of DOAC in PAD

Impact of Novel Therapies Around the World

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